Doctorado en Ciencias de la Salud

Active Biopeptides from Spanish dry-cured ham: From in vivo to in vitro

Cardiovascular Disease (CVD) has traditionally been related to risk factors. However, a significant body of scientific data has revealed another layer of complexity, pointing to the need for a healthier diet and regular exercise in order to increase protection. Therefore, there is a clear need and a substantial market opportunity for developing new foods and beverages with proven benefits for cardiovascular health. Bioactive peptides display distinct bioactivities in vitro: ACE inhibition, DPPIV, antioxidant, antimicrobial etc. In this line, there are numerous reports of clinically significant effects of consuming bioactive peptides on blood pressure in humans which are also supported by reports in animal models of hypertension. This effect is the result of a flexible molecular behavior which allow them to easily interact with very distinct proteins/receptors in vitro and over the human body. However, few data can provide information on their specific molecular mechanism(s) and targets. And there is a great interest in decrypting molecular mechanisms of action of bioactive peptides in order to support cardiovascular-related health claims. Indeed, biological activity assessments have been almost exclusively limited to assays to detect antihypertensive, antioxidant and antiinflammatory effects of these bioactive peptides. The current seminary summarizes a whole research project were the biological activities of bioactive peptides from dry-cured pork ham have been tested in vivo and in vitro.

Modalidad
Online - Campus Virtual
Duración
3 horas
Fecha límite subida
30/09/2024
Enlaces

Responsable de evaluación e impartición

Dra. Silvia Montoro García

  • Responsable de impartición

Dra. María del Mar Martínez Senac

  • Responsable de evaluación
1. There is access to these seminars through Portal del Doctorando, activity Seminarios de Investigación (Research seminars). There are three blocks (Ciencias Médicas - Medical Sciences, Nutrición y Tecnología Alimentaria- Nutrition and Food technology, and Inglés- English language) to choose seven seminars from any of these three blocks. 2. Seminars could be carried out at any time (before the deadline stablished by EIDUCAM). 3. For each seminar, students must view the recording and the PDF presentation. After this, two tasks must be accomplished: •A test questionnaire. Once it is filled in and sent, it will be corrected automatically. Only if all the questions are answered correctly (there will be five attempts to achieve it), there will be acces to the next task. •Write and submit a report in PDF format about the content of the seminar. This report will consist in an aproximately 600 words summary and must include three bibliographic references (as Vancouver or APA Recommendations) related to the Seminar subject area. 4. The responsible person of this activity will correct the report and qualification (0/10, if failed or 10/10 if pass) will be published. If it is failed, the student must read the observations, repeat the report and sent it again before the deadline (unlimited sending). 5. Once the evaluation is finished, a certificate will be sent for each passed seminar. The student must load the certificate to the corresponding activity in LAUREA, and it will be validated by his/her tutor.