Doctorado en Ciencias de la Salud

New Cell Therapies

The use of new cell therapies has taken a major step forward in recent years. The need for a link between the basic sciences and the possibility of applying this research directly in the patient is the key to success. The use of Human Induced Pluripotent Pluripotent Stem Cells (hiPSCs) would make it possible to carry out personalized medicine, which allows tissue or organs to be generated from the patient's own cells, thus avoiding possible rejections or complications of immunosuppression strategies. Current studies aim to develop a specific humanized hiPSC pancreas in an apancreatic pig by complementing interspecific blastocyst. The clinical implications of this technique extend beyond experimental models. The objective of the current studies is not only to obtain a human pancreas in the porcine species, but also to obtain the organ that the patient needs. The CRISPR Cas9 system is only applied to cells that divide. But since November 2016, Dr. Izpisua's team has started to use a modification of the CRISPR Cas9 technique by means of the Homology Independent Targeted Integration (HITI) method, by which he has been able to introduce DNA in a specific location of the cell genome that does not divide. This has opened up new avenues for basic research and also for the treatment of monogenic diseases. GOAL: Know new cell therapies

Modalidad
Online - Campus Virtual
Duración
3 horas
Fecha límite subida
12/07/2024
Enlaces

Responsable de evaluación e impartición

Dra. Mª Llanos Martínez Martínez

  • Responsable de impartición

Dra. María del Mar Martínez Senac

  • Responsable de evaluación
1. There is access to these seminars through Portal del Doctorando, activity Seminarios de Investigación (Research seminars). There are three blocks (Ciencias Médicas - Medical Sciences, Nutrición y Tecnología Alimentaria- Nutrition and Food technology, and Inglés- English language) to choose seven seminars from any of these three blocks. 2. Seminars could be carried out at any time (before the deadline stablished by EIDUCAM). 3. For each seminar, students must view the recording and the PDF presentation. After this, two tasks must be accomplished: • A test questionnaire. Once it is filled in and sent, it will be corrected automatically. Only if all the questions are answered correctly (there will be five attempts to achieve it), there will be acces to the next task. • Write and submit a report in PDF format about the content of the seminar. This report will consist in an aproximately 600 words summary and must include three bibliographic references (as Vancouver or APA Recommendations) related to the Seminar subject area. 4. The responsible person of this activity will correct the report and qualification (0/10, if failed or 10/10 if pass) will be published. If it is failed, the student must read the observations, repeat the report and sent it again before the deadline (unlimited sending). 5. Once the evaluation is finished, a certificate will be sent for each passed seminar. The student must load the certificate to the corresponding activity in LAUREA, and it will be validated by his/her tutor.